Pokémon: Mewtwo Strikes Back—Evolution

A team of scientists use the DNA of a rare Pokemon, Mew, to create the world's strongest Pokemon, Mewtwo. Not wanting to be used as an experiment, Mewtwo uses its psychic powers in a violent rage to destroy the scientists who created it. Mewtwo then tries to learn how to focus his powers with the aid of Giovanni, the man who funded the scientists' operations, but discovers that it is being used again. So Mewtwo decides to find its own purpose in life, and carry out its revenge on humans by destroying life on earth by using a deadly storm. Ash Ketchum and a group of other Pokemon Trainers are summoned by Mewtwo to have a battle with it, but they soon discover that they're only being invited so Mewtwo can clone their Pokemon for it's own purposes. Ash then tries to find a way to stop Mewtwo's plot before it can be carried out. Note: Originally screened in theaters as 75 minutes, a "complete version" was broadcast on TV the following year shortly before the release of Pokémon the Movie 2000, adding a reconstructed storytelling of Ash and Pikachu's first meeting to its runtime making it 85 minutes.

The Team Rocket leader, Giovanni, has found Mewtwo in a remote area of the Johto region. As Giovanni tries to re-capture Mewtwo, Ash and his friends are kidnapped by Domino, a new Team Rocket member, while trying to rescue Pikachu from Jessie and James. The Clone Pokemon are also captured and are then used as bait for Mewtwo. The situation then becomes a battle between the wills of Mewtwo and Giovanni; and Mewtwo also tries to discover if it and the clones have a purpose in life, even though they are products of science.

The 16th Pokémon movie and the 3rd "Best Wishes!" movie.

The original story is set before Mewtwo meets Satoshi and his friends in the upcoming film's storyline. It will focus on Mewtwo's history, goals, and how it became the strongest Pokémon.