Ameku M.D.: Doctor Detective

Nagumo Keiichirou was a genius high-school detective. No case was complex enough for him. But what happens to genius detectives when they get older? Now 35, with bad hips, running a failing detective agency with no cases to solve and struggling to pay the rent, he's at a dead end. In comes a high school girl in his office who says she wants to work with him. With her help, will the out-of-touch, old-fashioned Nagumo get back the fire of his youth?

Haruka Nishikikoji is an overweight doctor that never seems to attract any girls. Fate finds a way as he lands a job as a doctor in an elementary school, wherein his workplace can be found on top of the schools' roof and the actual clinic looks like a medieval castle. Just when everything seems to go downhill, a surprise came one day, her first love Koizumi Miyuki, applies as her soon to be nurse.

At the young age of 11, Kotoko Iwanaga was abducted by youkai for two weeks and asked to become their "God of Wisdom," a mediator between the spirit and human worlds, to which the girl quickly agreed but at the cost of her right eye and left leg. Now, six years later, whenever youkai wish for their problems to be solved, they make their way to Kotoko for consultation. Meanwhile, Kurou Sakuragawa, a 22-year-old university student, has just broken up with his girlfriend after he fled alone when the two encountered a kappa. Seeing this as her chance to become closer with him, Kotoko immediately makes her move, hoping to get married to Kurou one day. However, she quickly realizes there is something more to Kurou. With this knowledge, she asks for his help in solving the various issues presented by the supernatural, all the while wishing her newfound partner will eventually reciprocate her feelings.

As long as hearts exist inside people, there will always be those who suffer. And then something "strange" enters their mind and causes a strange disease to manifest itself in the body. The illness, which is called a "mystery disease" is unknown to most, but certainly exists. There is a doctor and apprentice who fights the disease, which modern medicine cannot cure. His name is Ramune. He acts freely all the time, is foul-mouthed, and doesn’t even look like a doctor! However, once he is confronted with the mysterious disease, he is able to quickly uncover the root cause of his patients' deep-seated distress and cure them. And beyond that...