Asa Made Jugyou Chu!

Otoboku 2 begins about two years after Mizuho's graduation. The main protagonist Chihaya Mikado was truant at his school because of harassment in the school and of a distrust in men. His mother cannot bear to watch him be in trouble, so she makes him transfer to Seio Girl's School, her old school. He dresses as a girl and introduces himself as Chihaya Kisakinomiya. Chihaya meets another protagonist Kaoruko Nanahara, who once rescued him from a playboy, and he begins to live in the dormitory building. He becomes the focus of public attention due to his attractive face and figure, and due to high grades at studies.

Does being the only guy in an all girl school sound like paradise? It might be, if the girls knew you were a guy, but to stay in school teenage pervert Banji can't let can't let anyone find out his chromosomes don't match. Banji's status conscious parents want him to go to a good school, but not enough to spend the money on a good co-ed school. Now, in addition to studying math and science, Banji has to learn how to put on a bra and makeup. His life has become a living hell. Not only is he at the bottom of the social pecking order, he must also got to conceal his inner-masculinity from the pretty classmate girl who's stolen his heart while avoiding the female bullies who threaten to expose his less-than-feminine charms in the locker room.

Hanaoka high school is an all girls' school, and the girls were pretty excited when they heard that boys were admitted into their high school. Smart and elegant boys, that's in their fantasy. However, in reality, the boys who were actually admitted are from the countryside and not smart at all, leave alone being elegant. And in fact, two of them are dirty perverts...

It is the start of Takatoshi Tsuda's second year as the put-upon vice president of the student council and his sister Kotomi is entering school as a first year. New friends and double entendres are made.