BLAME!

Based on the manga Blame! by Nihei Tsutomu. In a city that is said to have thousands of levels, making it impossible to tell the sky from the ground, the mysterious Killy wanders the bizarre and foreboding levels of this mega-structure, where the boundaries between machine and living organism have been obscured.

Based on the Blame! manga series by Tsutomu Nihei.

In the great city of Metropolis, severe community structures and prejudice dominate a world where humans and robots live together. Unrest and violence increase with each new day. Searching for the scientist Dr. Laughton, suspected to violate human rights by trading organs, the Japanese detective Shunsaku Ban and his nephew Kenichi arrive at Metropolis. In the scientist's laboratory, Kenichi discovers a girl without any memory of her past life. He decides to help her, so they run away together. His uncle follows him and penetrates the dark secrets of the city to find Duke Red, the man ruling from the shadows. Meanwhile, Kenichi desperately tries to protect the mysterious girl from the people hunting her. However, Duke Red and his adoptive son have their own deep reasons for chasing the girl. These reasons are connected to her true identity and the struggle for the domination of Metropolis...

In the future, utopia has finally been achieved thanks to medical nanotechnology and a powerful ethic of social welfare and mutual consideration. This utopia isn't perfect, and three young girls stand up to totalitarian kindness and super-medicine by attempting suicide via starvation. It doesn't work, but one of the girls—Tuan Kirie—grows up to be a member of the World Health Organization. As a crisis threatens the harmony of the new world, Tuan rediscovers another member of her suicide pact, and together they must help save the planet...from itself.